2025 Honda Odyssey vs. 2025 Toyota Sienna: 5 Key Differences originally appeared on Autoblog.
If you’re shopping for a minivan, there are only a few choices to pick from, including the Chrysler Pacifica, the Kia Carnival, the Honda Odyssey, and the Toyota Sienna. If you are familiar with the minivan world, then you know that the last two choices are by far the most popular. And if you’re shopping between the Sienna and Odyssey, it could be tough to pick the right one for you.
The 2025 Toyota Sienna offers up a hybrid powertrain, the availability of all-wheel drive, and a host of in-cabin technologies that differentiate it from the rest. The 2025 Honda Odyssey, on the other hand, has a six-cylinder engine and is front-wheel-drive only, but it has sporty driving dynamics that you normally wouldn’t find in a minivan. Add to that the myriad of comfort and convenience features that it offers, and we wouldn’t blame you for resorting to a coin toss to pick between these two front-runners.

However, if you really are trying to pick between the Honda Odyssey and Toyota Sienna, there are a handful of differences that should be brought to your attention to help you decide. Here are five key differences between the two.

#1. Powertrain: V6 vs. Hybrid
A V6 engine has always powered the Honda Odyssey, and not much has changed for 2025. Under its hood is a 3.5-liter V6 engine that produces 280 horsepower and 262 lb-ft of torque, which is more than enough to get the family hauler moving quickly. And while most drivers can appreciate a good V6 and the power it emits, the stark reality is that it still achieves only up to 19 mpg in the city and 28 mpg on the highway. That’s not bad for a heavy minivan, but it doesn’t hold a candle to the Toyota Sienna’s specs.
The 2025 Toyota Sienna is motivated by a different setup, which consists of a 2.5-liter, four-cylinder engine that’s mated to a hybrid powertrain. Combined, the unique configuration is good for 245 horsepower, which is noticeably less than the Odyssey’s powerplant. However, fuel economy is where the Sienna really shines, as the EPA estimates that it can achieve up to 26 mpg in the city and on the highway. In real-world testing, many drivers have been able to match those estimates, making the Sienna a true winner when it comes to fuel-efficient motoring.

#2. Available All-Wheel-Drive
If you live in an area that sees snow for part of the year, or you plan to drive your minivan on some minor off-road trails, the Toyota Sienna is the better pick. The Sienna comes standard with a front-drive configuration, but it is also available with an all-wheel drivetrain, which makes it a more capable choice than the Honda Odyssey.

#3. Interior Configuration and Technology
Both of these minivans offer similar technology, including a premium audio system, wireless Apple CarPlay and Android Auto, and the availability of rear entertainment systems. However, they differ when it comes to their interior configurations. The Honda Odyssey features a Magic Slide second row for flexible configuring, while the Sienna offers ottoman-style captain’s chairs for a more premium lounge-like experience.

#4. Infotainment and Features
As stated, both of these minivans have all the tech-savvy goods that families need, including large touchscreen infotainment systems and entertainment features. However, they differ when it comes to some of their in-cabin technologies. For example, the Honda Odyssey is available with CabinTalk, which allows the driver to talk to the second- and third-row occupants through the speakers. That makes it easier for parents to reprimand their kids without having to shout. Also, the Odyssey has a CabinWatch feature built into the infotainment system, which allows them to see the second row. It’s perfect if you have young kids or babies to keep your eye on.

The Toyota Sienna has its own set of features up its sleeve, which includes a large nine-inch touchscreen infotainment system, a digital mirror, and a vacuum cleaner. There is even a cooler available for drinks and other food items you need to keep cool while on the go.
#5. Styling and Trim Options
There is no denying that both of these minivans look like, well, minivans. However, both automakers have stepped up their styling efforts. The Honda Odyssey features a more conservative and clean exterior style, which gives it a classic minivan appearance. The Sienna has a bolder and more angular style, which makes it look a little more adventurous, especially in Woodland Edition guise. Ultimately, the Sienna has more visual personality and outdoorsy trims, while the Odyssey feels more understated and traditional.

Final Thoughts
Selecting the right minivan for you and your family can be challenging, but narrowing down your choices is a good starting point. If you end up getting down to the 2025 Toyota Sienna and the 2025 Honda Odyssey by a process of elimination, then these five differences could help you make the best decision. Of course, we recommend driving both to make the best choice.
2025 Honda Odyssey vs. 2025 Toyota Sienna: 5 Key Differences first appeared on Autoblog on Aug 5, 2025
This story was originally reported by Autoblog on Aug 5, 2025, where it first appeared.
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